CIN-109, CIN-110, CIN-209 and CIN-210 are monotherapies and combination treatments for obesity.
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GDF-15 Analog
GDF-15 / GLP-1 – Dual Agonist
Gastroparesis
Deudomperidone (CIN-102) is a Dopamine 2/3 antagonist with prokinetic and antiemetic effects.
IBS-D
CIN-103 is a novel formulation of phloroglucinol modified to enhance the pharmacokinetic properties to sustain the therapeutic exposure for patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
Oncology
CIN-108 is a small molecule inhibiting defective in cullin neddylation 1 (DCN1) from binding in the pocket where it is necessary to promote neddylation and interfere with the progression of multiple solid tumors.
Type 1 Diabetes
An oral small molecule, adjunct therapy to insulin in patients with type 1 diabetes (T1D).
Retromer Therapeutics is developing novel medicines to treat neurodegenerative diseases.
